Antiretroviral (ARV) Therapy in Resource Poor Countries: What do we Need in Real Life?
نویسندگان
چکیده
Significant progresses have been made in the last 5 years towards the ultimate goal to provide universal access to care for all HIV/AIDS patients needing antiretroviral treatment in resource-poor countries. However, many barriers are still to be overcome, including () cost of care for the individual, () stigma, () lack of qualified human resources and infrastructure, especially in the rural setting, () rescue drugs for failing patients and () pediatric formulations. Priority actions to be promoted if the fight against HIV/AIDS is to be successful include: (i) promoting access to care in the rural areas, (ii) strengthening of basic health infrastructures, (iii) waiving of users' fee to get ARV, (iv) a larger variety of drugs, with particular regard to fixed dose combination third line drugs and pediatric formulations, (v) local quality training and (vi) high quality basic and translational research. While the universal access to HIV care is crucial in developing countries, a strong emphasis on prevention should be maintained along.
منابع مشابه
Economic evaluation of weekends-off antiretroviral therapy for young people in 11 countries
OBJECTIVES To analyze the cost effectiveness of short-cycle therapy (SCT), where patients take antiretroviral (ARV) drugs 5 consecutive days a week and have 2 days off, as an alternative to continuous ARV therapy for young people infected with human immunodeficiency virus (HIV) and taking efavirenz-based first-line ARV drugs. METHODS We conduct a hierarchical cost-effectiveness analysis based...
متن کاملSetting Priorities for Government Involvement with Antiretrovirals
This paper examines four questions posed by economic analysis to help set priorities for government involvement with antiretroviral therapy for people living with HIV/AIDS. The main focus is on making decisions about policy relating to ARVs in developing countries where the needs are greatest and resource constraints are most binding. While the answers may vary considerably depending on individ...
متن کاملSimplifying and adapting antiretroviral treatment in resource-poor settings: a necessary step to scaling-up.
Access to antiretroviral (ARV) therapy for patients in developing countries has become an increasing global public health and political concern in recent years. Both donor governments and those of high-burden countries agree that treating AIDS is a major priority. Efforts are underway in many countries to increase the numbers receiving ARV treatment, and the level of international funds committ...
متن کاملContextual and psychosocial influences on antiretroviral therapy adherence in rural Zimbabwe: towards a systematic framework for programme planners
Great progress has been made in achieving universal access to antiretroviral therapy (ART). However, for successful viral suppression, patients must adhere to rigid and complex treatment regimens. With three quarters of antiretroviral (ARV) users in Africa adhering successfully, African countries have achieved extraordinary levels of adherence given the levels of poverty in which many ARV users...
متن کاملResistance to antiretroviral treatment in Gabon: need for implementation of guidelines on antiretroviral therapy use and HIV-1 drug resistance monitoring in developing countries.
The protease and reverse transcriptase (RT) genes were studied in antiretroviral (ARV)-experienced and drug-naive HIV-1-infected individuals in Libreville, Gabon. We have shown, although on a limited number of samples that in 58% (11/19) of the patients, with a mean of 17.7 months of ARV drug experience, major mutations inevitably inducing resistances to ARV drugs were present. Resistance was m...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 4 شماره
صفحات -
تاریخ انتشار 2010